Wrist-Mounted Vital Signs Monitor from Empirical Technologies CareTaker® is a wrist mounted complete vital signs monitor weighing 105 grams. It has been validated against over 400 hours of radial and central catheters to track beat by beat blood pressure (cNIBP) and ECG accurate heart rate. Additional trials verified that CareTaker detects blood loss of one pint. Other trials showed that CareTaker measures respiration rate and beat by beat arterial stiffness. Two modifications in prototype production allow the tracking of SpO2 and near-core body temperature. CareTaker uses a low pressure, below diastole, skin friendly polyurethane cuff around a finger or thumb and, for SpO2, a separate distal finger cuff. Temperature is taken in the axilla using a small patch and Bluetooth low energy (BLE) to transmit the temperature every minute for a week whereupon the patch is disposed. CareTaker slaves up to eight BLE enabled device such as a bathroom scale, glucometer, or future biomedical devices for specific disease identification. The heart rate function allows determination of all arrhythmias such as atrial fibrillation, but without the electrodes that, when removed, often tear the skin of older people. The new prototypes contain a cellular radio that reaches 99% of the US population. Simply by putting the cuff on and pushing a button, all five vital signs and others are continuously transmitted through a HIPAA data tunnel to a secure server. No confusing cell phones connections or pairings are necessary nor any hubs or extra equipment. The device works as well at home as on the interstate highways; one device does it all. Cloud data is available through Apps that are downloaded to cell phones, PCs, and tablets. Both real time and trend data, from home sleep studies for instance, are instantly available to qualified caregivers. All data is locally processed using an on-board ARM processor so that the data rate is almost zero, dramatically lowering subscription costs. A battery charge lasts for over 15 hours. SpO2 is only measured every 20 seconds and the pulse rate is not measured using the oximeter since it excessively uses battery energy and the results are not good enough for heart rate variability. CareTaker will cost as much as a smart phone and can be carried around in a purse or pocket. For sleep studies it should replace polysomnography, determine the nocturnal dip, and discover dangerous and prevalent nocturnal hypertension. CareTaker is a complete vital signs monitor with real time observation at any distance, greatly reducing emergency room visits. There is solid evidence that CareTaker can enable predictive cardiology. In a small blind trial, CareTaker detected and located five of five aortic aneurisms. The theory behind CareTaker is new, but supported in peer reviewed literature. Basically CareTaker decomposed each pulse arriving at the finger into several constituent pulses that occur due to partial pulse reflections near the renal arteries at the aorta and another at the iliac artery bifurcation. It was developed using SBIR funding for combat casualty care from the Office of Naval Research and the Office of the Secretary of Defense.